The transgenic construct encodes a deletion in fat-specific element(FSE)region of human GPD1 promoter (deletes from -258 to -135, or 124 bp). A second strain, d124B, was also created (2-5 copies in each) and two shorter deletion (36 bp) mutants (d36A, d36B) were generated. (J:135002)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x SJL/J)F2
--
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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