A 3.4 kb fragment including all coding exons (exons 2- 5) was flanked with loxP sites and an adenoviral splice acceptor site fused to a cDNA encoding eGFP was inserted downstream of the second loxP site. In vivo cre-mediated recombination resulted in deletion of exons 2-5 and expression of eGFP under control of the endogenous promoter. (J:139030)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion, Intragenic deletion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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