A loxP site was inserted into intron 4 and an FRT and loxP site flanked neomycin resistance gene cassette was inserted onto intron 6. Flp-mediated recombination was used to remove the neo cassette leaving exons 5 and 6 floxed. (J:137138)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count