This mutation was identified among progeny of an ENU-mutagenized male mouse. Mice heterozygous for both this mutation and the classic dilute mutation, Myo5ad, exhibit a coat color similar to that of homozygotes for the present mutation, and intermediate between coat colors of wild-type and homozygous dilute mice, suggesting this may be a hypomorphic allele of Myo5a. However, the present mutation has not been mapped, nor has sequence analysis been done of the Myo5a gene carried by these mutant mice.

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6JJcl
Chemically induced
Undefined
Recessive
--
--
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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