A floxed neo cassette and EGFP coding sequence were inserted into exon 3. Transient cre expression in ES cells was used to remove the cre cassette. EGFP is expressed in insulin-producing beta cells of the islet of Langerhans. (J:137004)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count