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Targeted insertion of thymidine kinase into the C57BL/6J derived Chromosome 5 Dpp6 locus in the v6.4 ES cell line was followed by 400 Gy of gamma radiation, FIAU selection, and injection into C57BL/6J blastocysts. This deletion includes D5Mit348 through D5Mit389 and falls outside of the Wolf-Hirschhorn syndrome critical region. (J:67077)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
