Log In|Sign Up
EN
Targeted insertion of thymidine kinase into the C57BL/6J derived Chromosome 5 Htt locus in the v6.4 ES cell line was followed by 400 Gy of gamma radiation, FIAU selection, and injection into C57BL/7J blastocysts. The deletion includes the full Wolf-Hirschhorn syndrome critical region and extends to include D5Mit148 and Qdpr. (J:67077)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
