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The mouse alpha-cardiac MHC promoter drives expression of a human TGF-beta1 cDNA encoding a cysteine-to-serine substitution at amino acid residue 33. High levels of transgene-derived mRNA were detected in heart. In addition to line 3, transgenic lines 4, 5 and 6 were also established. (J:61263)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
