A termination codon followed by a loxP site was inserted at the first codon of alternative exon CR3b which is specific to the B type isoforms. A floxed neo was also inserted for selection purposes and subsequently removed by germ line, cre-mediated recombination. (J:136920)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count