Cre mediated recombination was used to remove the floxed open reading frame leaving the cre/ESR1 fusion intact. Neurog3 expression is abolished and the cre/ERT fusion protein is expressed under the control of the endogenous Neurog3 promoter. (J:136131)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count