A cassette containing a floxed version of the open reading frame followed by a cre/ERT fusion gene was inserted to replace the endogenous gene. This allele expresses a normal Neurog3 protein unless exposed to Cre recombinase, which then causes recombination of the loxP sites and expression of the cre/ERT fusion. (J:136131)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion
--
1
1
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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