A tk/neo selection cassette flanked by two loxP sites was inserted 230 bp upstream of exon 8 replacing a 222-bp genomic sequence. A third loxP site was inserted 84 bp downstream of exon 8. (J:134709)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count