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A loxP site was inserted into exon 1 upstream of the initiation codon, and an frt-flanked neomycin resistance cassette with a 3' loxP site, followed by an internal ribosomal entry site (IRES) and the coding sequence for green fluorescent protein (GFP), was inserted into the second exon downstream of the stop codon. The neo cassette was removed by germ line, flp-mediated recombination. This is a conditional knockout (floxed) allele and a reporter allele. (J:136241)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
