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This transgene expresses a mutant form of murine Cryab containing a missense mutation (R120G). This missense mutation acts in a dominant-negative fashion. In addition to transgenic line 708, lines 25 and 134 were also produced. The transgene copy number of this line is 1. (J:133093)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
