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The transgene is composed of a 1.9-kb rat AGT cDNA coupled to a 5.8-kb mouse alpha-MHC gene promoter. 1.6 kb of the rabbit bIVS2 intronic sequences are also included. RT-PCR analysis indeicated that this transgene was expressed specifically in the heart. Five copies of the transgene are integrated in TG153 transgenic mice. (J:129140)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
