LoxP sites were introduced 5' of the Mirn17 gene and 3' of the Mir92-1 gene. The floxed region was followed by an Frt-flanked neomycin cassette. The entire cluster, including Mir17, Mir18a, Mir19a, Mir20a, Mir19b-1, and Mir92-1 is flanked by the inserted loxP sites. (J:134861)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
Insertion
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--
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6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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