The mouse open reading frame was replaced with the human one and a floxed neo cassette. Germ line, cre-mediated recombination was used to remove the neo cassette. This is a null allele and a knock in allele. (J:135789)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count