A Tcf-reporter construct was generated containing the lacZ gene downstream of a c-Fos minimal promoter and three consensus Tcf-binding motifs. Binding of a beta-catenin-Tcf complex activates the expression of lacZ. (J:76273)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count