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A 45-kb fragment containing the intact human PON1 gene with 10 kb of 5'-flanking and 10 kb of 3'-flanking sequences was used for the production of Tg mice. This transgenic line carried ~3 copies of the transgene, as determined by Southern blot analysis. (J:103311)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
