Tg(Myh6*)1Lnwd

Nucleotides 2,381 to 2,563 were deleted from published rat alpha-cardiac MHC and then fused to a COOH-terminal myc-tagged MHC fragment. This mutant cDNA was expressed under the control of a 3.3 kb of rat a-cardiac MHC promoter and the cDNA was followed by the mouse beta-globin terminator. The encoded protein lacks the light chain binding domain. (J:55938)