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Nucleotides 2,381 to 2,563 were deleted from published rat alpha-cardiac MHC and then fused to a COOH-terminal myc-tagged MHC fragment. This mutant cDNA was expressed under the control of a 3.3 kb of rat a-cardiac MHC promoter and the cDNA was followed by the mouse beta-globin terminator. The encoded protein lacks the light chain binding domain. (J:55938)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
