Log In|Sign Up
EN
A rat myosin heavy chain promoter drives the expression of a rat cardiac alpha myosin heavy chain (Myh6) cDNA that was modified by mutating residue 1445 from a G to an A, and the deletion of codons 468-527. This resulted in a R403G substitution and a deletion in the putative actin binding domain in the encoded protein. This transgenic line exhibits a strong phenotype. (J:36522)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
