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The transgene construct consists of about 5.5 kilobases of the mouse alpha-myosin heavy chain promoter, including the first 2 exons and part of the third, followed by the human TNNT2 cDNA (876 base pairs) modified to express a I79N mutation, and a 630-base pair 3'-untranslated region from the human growth hormone transcript. (J:67284)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
