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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
Amyotrophic Lateral Sclerosis 1
USH2A c.8559-2A>G
Cystic Fibrosis
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Gene editing
Gp1bb
tm2Frla
Alias:
GPIbbetadeltaIC
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Basic Information
Phenotypes
References Literature
A floxed neo cassette was inserted upstream of the coding region and the coding region was replaced with one in which the intracellular domain has been deleted. Cre mediated recombination was used to remove the neo cassette. (J:135065)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3793297
129S2/SvPas
Targeted
Insertion, Intragenic deletion
--
1
5
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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