The floxed exon 2 and 3 of Egln1tm1Kael were removed via cre-mediated recombination by mating with Tg(EIIa-cre)C5379Lmgd mice. Egln1 mRNA and protein are undetectable in MEFs isolated from E12.5 embryos. (J:132718)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count