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Exons 3 to 6, which encode a portion of the signal peptide and nearly half of the coding sequence of the gene, were deleted by homologous recombination. Analysis of the founder lines confirmed that the targeting strategy had successfully given rise to the expected mutant allele. (J:134343)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
