A 10 kb fragment including the start methionine codon in exon 1 through 208 bp downstream of the stop codon in exon 3 was replaced with a frt-flanked targeting cassette. The targeting cassette was subsequently removed leaving a frt recombinase site in place of the coding region. (J:134640)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count