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Two expression cassettes, one containing a 17.5 kb Tcr Valpha2.3-JalphaDK1 rearrangement and the other containing a 19.5 kb Tcr Vbeta8.3-Jbeta2.5 rearrangement, were coinjected into fertilized eggs. The injected fragments are specific for the LCMV GP-derived epitope P13 (amino acids 61-80) in the context of H2-IAb. Two transgenic mouse lines (referred to as Smarta1 and Smarta2) were derived from a single transgenic founder. Each sub-line was given its own allele because of phenotypic differences between the sub-lines. (J:92228)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
