A neomycin selection cassette has been inserted upstream of exon 1, and the neo cassette and exons 1 and 2 are flanked by loxP sites. Expression of Cre recombinase in mice bearing this allele results in excision of both exons and the selection cassette. (J:134373)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count