Part of exon 2 through the end of the coding region in exon 5 was replaced with a GFP reporter gene and floxed neo cassette. The absence of transcript was confirmed by qantitative RT-PCR on P6 brain extracts. This is a reporter and null allele. (J:134210)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NTac)F1
Targeted
Insertion, Intragenic deletion
--
1
1
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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