The gene trap vector pGT1lxf that contains the beta-geo cassette was inserted between exon 10 and 11. This allele is a reporter allele and a hypomorphic allele with reduced expression in the brain (80% reduction), liver (70% reduction) and spleen (50% reduction) of homozygotes as detected by semi-quantitative RT-PCR. (J:133892)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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