The transgene consists of a 25 Kb fragment from BAC 284H12, that contains mouse Eno2 driving neural-specific expression of an IRES-EGFP-cre cassette, which was inserted into the last exon of the locus. Two lines were created with neural cre expression in different subsets of neurons. This line contains 5 copies of the transgene and is expressed in most basket cells, stellae cells, Purkinjie cells and neurons of the deep cerebellar nuclei but few granule cells and Golgi cells in the granule layer (J:133505)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C3H/HeN x C57BL/6NCr)F2
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Insertion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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