The transgene consists of a 25 Kb fragment from BAC 284H12, that contains mouse Eno2 driving neural-specific expression of an IRES-EGFP-cre cassette, which was inserted into the last exon of the locus. Two lines were created with neural cre expression in different subsets of neurons. This line contains 4 copies of the transgene and is expressed in a subset of Gogi cells and a few cells in the granule and Purkinjie cell layers. (J:133505)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count