The entire coding region (exons 2 through 4) was replaced by a tau-lacZ and floxed hygro cassette. The hygro cassette was removed by transient cre expression in ES cells. This is a null allele because it lacks the coding region. (J:133341)
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The entire coding region (exons 2 through 4) was replaced by a tau-lacZ and floxed hygro cassette. The hygro cassette was removed by transient cre expression in ES cells. This is a null allele because it lacks the coding region. (J:133341)