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EN
A targeting construct introduced into the locus a floxed neomycin resistance and STOP cassette, the cDNA for a hyperactive version of human Stat3 (A661C and N663C; STAT3C) with a FLAG-tag, and an FRT-flanked IRES-EGFP reporter cassette. In the presence of Cre recombinase, the STOP element is removed and bicistronic expression of STAT3 and GFP occurs. (J:133218)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
