A floxed neo cassette was inserted downstream of exon 4 and an additional loxP site was inserted downstream of exon 2. The neo cassette was removed by germ-line, cre-mediated recombination resulting in a floxed exon 3 and 4. (J:133084)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count