Log In|Sign Up
EN
The toffee mutation corresponds to T-to-C transition in the donor splice site of intron 9 (GTAATT->GCAATT) (nucleotide position 16609 in the Genbank genomic region NC_000073) that destroys the splice site, resulting in the usage of a downstream sequence within intron 9 for splicing. Thus, 23 nucleotides from the 5' end of intron 9 are inserted into the transcript and the reading frame shifts folowing the insertion. (J:133272)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
