A gene trap vector with a strong splice acceptor and a beta-geo cassette inserted into the gene. This insertion created a fusion protein where the first 1,767 amino acids of the protein containing the extracellular domain, the transmembrane domain, and a small portion of the intracellular domain are fused to the reporter cassette. Reporter expression is detectable in the embryonic heart starting at E10.5. (J:132939)
Basic Information
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count