A gene trap vector with a strong splice acceptor and a beta-geo cassette inserted into the gene. This insertion created a fusion protein where the first 1,767 amino acids of the protein containing the extracellular domain, the transmembrane domain, and a small portion of the intracellular domain are fused to the reporter cassette. Reporter expression is detectable in the embryonic heart starting at E10.5. (J:132939)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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