The cre recombinase coding sequence and SV40 polyadenylation signal followed by an frt-flanked PGK-neo selection cassette (in the opposite orientation) was inserted into exon1 by homologous recombination of the Nanos3 gene in TT2 ES cells. Expression is detected at E7.75 in germ cells during the migration stage and after entry into the gonad. (J:136687)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NCrlj x CBA/JNCrlj)F1
Targeted
Insertion
--
1
--
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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