Germline deletion of the gene locus was achieved by crossing Traf3tm1Rbr mice with Tg(Zp3-cre)3Mrt mice that express Cre in oocytes. Genomic PCR confirmed deletion of exon 4 in the gene locus. (J:132877)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count