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A linearized PAC clone containing the human CD34 gene and 110 kb of promoter sequence and 26 kb of downstream sequence was used as a transgene. Two copies of the transgene inserted and expression was detected in numerous tissues with highest levels detected in the bladder, heart, lymph nodes, and lungs. Expression at the RNA and protein levels was very similar to the endogenous mouse Cd34 gene. (J:132476)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
