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The Lck promoter with the Emu enhancer drives expression of a cDNA encoding a constitutively active Stat5b with point mutations that result in replacement of histidine with arginine at position 299 and serine with phenylalanine at position 711. This mutation results in constitutive phosphorylation of tyrosine 699. (J:86610)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
