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EN
ENU mutagenesis resulted in a nucleotide substitution at codon 112 of AAC to GAC that created an amino acid substitution of an aspartic acid for an asparagine at position 112 (N112D). This mutation occures in the coenzyme-binding domain and results in a decreased enzymatic activity to 58% of wild-type in heterozygotes. (J:45877)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
