A cassette containing an IRES, human AFP and polyadenylation signal was inserted into the 3' untranslated region along with a floxed neo cassette and resulted in a duplication of exon 13 through part of exon 18. The neo cassette was removed by transient cre expression. Expression of AFP was confirmed by a quantitative immunoassay. (J:132096)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count