A cassette containing a splice acceptor, IRES, human AFP and a splice donor was inserted into intron 1 along with a floxed neo cassette. The neo cassette was removed by transient cre expression. Expression of AFP was confirmed by a quantitative immunoassay. (J:132096)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count