An frt-flanked neo cassette with a 5' loxP site was inserted downstream of exon 4 and an additional loxP site was inserted upstream of exon 1. Germ-line flp-mediate recombination was used to remove the neo cassette leaving exons 1 through 4 floxed. (J:131834)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count