Six nucleotides in intron 2 were replaced with a FRT-flanked neomycin resistance cassette and a loxP site. A second loxP site replaced 4 nucleotides in intron 5. Southern blot confirmed the presence of the mutant allele. (J:132141)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count