6.2 kb of sequence containing the upstream enhancer/promoter and 1.3kb downstream sequence containing exon 1 and part of exon 2 were used to drive Cre expression. Transgene expression was observed in numerous mesenchymal cells including fibroblasts, articular chondrocytes and myoblasts, skin keratinocytes, and underneath the epithelial layer of the gut. (J:131930)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x CBA
--
Insertion
--
--
--
18

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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