6.2 kb of sequence containing the upstream enhancer/promoter and 1.3kb downstream sequence containing exon 1 and part of exon 2 were used to drive Cre expression. Transgene expression was observed in numerous mesenchymal cells including fibroblasts, articular chondrocytes and myoblasts, skin keratinocytes, and underneath the epithelial layer of the gut. (J:131930)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count