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The gene locus was chosen due to its active transcription throughout T- and B- cell development. Germ-line Dbeta1 and Jbeta1.1 segments, their recombination signaling sequences and intervening intronic sequence were inserted between exon 1 and 2 of the gene locus. Southern blot analysis of T and B cells revealed germ-line and recombined versions of the knocked in gene segment. (J:131995)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
