Exons 2 through 7 were flanked with a single loxP site and a floxed neo cassette. The exons and neo cassette were removed by cre-mediated recombination in ES cells. The absence of protein product was confirmed by western blot analysis on spinal cord homogenates. (J:131957)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count