Exons 3 and 4 were removed by germ-line cre-mediated recombination. The ability of this allele to function as a null allele was confirmed by western blot analysis on total lysates of cells carrying the floxed allele and transduced with cre, in which case no protein products were detected. (J:131699)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count